Qian (Vivian) Liu, PhD

Zoonotic diseases (zoonoses) are infectious diseases that originate from animals and subsequently infect humans. RNA viruses are the primary etiological agents of human emerging pathogens, occupying up to 44% of all emerging human diseases. Paramyxoviruses are negative-stranded RNA viruses with great zoonotic potential. Members include established human pathogens (e.g. Measles virus) and emerging deadly zoonotic viruses (e.g. Nipah and Hendra viruses). My lab is interested in understanding the infection and transmission of zoonotic viruses in humans and animals. Specifically, we study the mechanisms of virus entry and assembly and how viruses hijack and/or evade host factors during these processes. By combining super-resolution imaging, novel fluorescence labelling, and optogenetic tools, we provide precise structural and behavioural information to dissect virus-host interactions during viral infection and transmission. Our research sheds light on novel antiviral development.